![]() Some other drugs, when broken down in the body, require the activity of the enzyme CYP3A4 in the small intestine, when drinking grapefruit juice can block the activity of this enzyme, causing the drug to be metabolized in the small intestine instead. ![]() More specifically, if you drink a lot of grapefruit juice while taking cholesterol-lowering statins, it can increase your risk of liver and muscle damage, eventually leading to kidney failure. Having questions and worries about a drug you have to take is normal, but try to get your information about medications from reliable resources and if you are worried make sure you always talk to your doctor, nurse or a pharmacist as they’ll be able to help you with this.Grapefruit interacts with drugs but not all of the above groups of drugs and the severity also varies from case to case, depending on the patient's medical condition, the type of drug and the amount of grapefruit juice given. Statins have been used to lower cholesterol for a long time but in recent years, there’s been a lot of controversial debate and news around this medication. Check with your healthcare team to find out what is appropriate for you. Statins should usually be stopped if you are planning a pregnancy or as soon as pregnancy is confirmed. Make sure you talk to your doctor about any other drugs you’re taking before you start taking statins. Statins can sometimes interact with other medicines and this can cause side effects too. Make sure you check the patient information leaflet that comes with your medicine for more information. That's because if you do have any side effects then you can deal with them in your own time and without extra pressure. You might want to start taking statins at the weekend or during a break from work. Like all medicines, statins can have side effects for some people. Your doctor will be able to suggest the best way forward, such as trying a different statin or a lower dose. Don’t stop taking your medication as your cholesterol might go up again. You can also check the patient information leaflet.
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